Jarrow Formulas 5-HTP 100mg
Jarrow Formulas 5-HTP 100mg - Image 2

Jarrow Formulas 5-HTP 100mg

Brand: Jarrow Formulas

Item # 790011150435

$30.99

Griffonia-derived 5-HTP to support your body’s serotonin & melatonin pathways

Jarrow Formulas Five-HTP delivers 100 mg of 5-hydroxytryptophan from Griffonia simplicifolia seed in a vegan capsule.
5‑HTP is the direct metabolic precursor to serotonin and is also used to produce melatonin—two messengers involved in mood, sleep, and daily rhythm.
It’s a simple, one‑capsule‑a‑day way to add this nutrient to your routine.

Why We Like It

  • Griffonia seed extract — sourced from a plant naturally rich in 5‑HTP.
  • Straightforward formula — 100 mg per capsule with vegan, gluten‑free excipients.
  • Easy to fit in — once‑daily capsule designed for use on an empty stomach.

Key Benefits

  • Provides 5‑HTP, the direct precursor to serotonin, which the body also uses to make melatonin.*
  • Supports everyday mood and sleep pathways without stimulants or botanicals.*
  • Pairs well with consistent sleep habits and wind‑down routines for holistic support.*

What’s Inside

  • 5‑HTP (from Griffonia simplicifolia seed) — supplies the intermediate the body converts to serotonin and melatonin.*
  • Vegetable capsule — hydroxypropyl methylcellulose shell.
  • Microcrystalline cellulose, magnesium stearate (vegetable), silicon dioxide — support capsule fill and stability.
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Supplement Facts & Suggested Use

Supplement Facts Amount per 1 capsule % Daily Value
5‑HTP (5‑Hydroxytryptophan) (from Griffonia simplicifolia) (seed) 100 mg †

Other ingredients: Microcrystalline cellulose, capsule (hydroxypropylmethylcellulose, water), magnesium stearate (vegetable source), silicon dioxide.

Free of: Wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts, and sesame.

Suggested Use: Adults take 1 capsule once daily on an empty stomach, or as directed by your qualified healthcare professional.

Important: Talk with your healthcare provider before use, especially if you take medications or supplements that affect serotonin (e.g., SSRIs, SNRIs, MAOIs, St. John’s wort, SAM‑e), are pregnant or nursing, or have medical conditions.

Additional Resources

  • 5‑HTP & Sleep in Older Adults — A randomized controlled trial explored daily 100 mg 5‑HTP and reported changes in sleep quality metrics over 12 weeks. Learn More
  • Depressed Mood Evidence Summary — A Cochrane review suggests potential benefit of 5‑HTP/tryptophan vs. placebo, while emphasizing the need for higher‑quality, modern trials. Learn More
  • Safety & Interactions — Memorial Sloan Kettering highlights cautions with antidepressants and other serotonergic agents due to serotonin syndrome risk. Learn More
  • General Supplement Use Tips — NIH Office of Dietary Supplements outlines questions to ask and how to choose quality supplements. Learn More
  • What 5‑HTP Is — ScienceDirect overview describes 5‑HTP as the intermediate between tryptophan and serotonin that bypasses the rate‑limiting step of synthesis. Learn More

Lifestyle Tips

Create a steady evening routine—dim lights, limit late caffeine, and keep a regular bedtime. If you’re using 5‑HTP for
sleep support, take it roughly 30–60 minutes before bed on an empty stomach. For daytime use, pair with a balanced
diet and movement to support overall well‑being. If you also use melatonin or other sleep aids, check with your
healthcare provider to avoid overlap.

Five‑HTP FAQs

What is 5‑HTP?

5‑Hydroxytryptophan (5‑HTP) is a compound the body uses to make serotonin and melatonin. As a supplement, it’s typically derived from Griffonia simplicifolia seed.

Can I take 5‑HTP with antidepressants?

Do not combine 5‑HTP with antidepressants or other serotonergic agents unless your prescriber is closely supervising; doing so may increase the risk of serotonin syndrome.

When should I take it?

Most people take 5‑HTP on an empty stomach. For sleep routines, many prefer it 30–60 minutes before bedtime.

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