XYMOGEN HistDAO

Brand: XYMOGEN

Item # 722537512503

$57.49

Support for healthy histamine metabolism

HistDAO® is designed for individuals who struggle with histamine-related discomfort. This unique formula provides the natural enzyme diamine oxidase (DAO), which helps break down histamine in the digestive tract. By supporting your body’s ability to process histamine from foods, HistDAO® can help reduce symptoms like flushing, headaches, and digestive upset that often come from histamine-rich meals.

Why We Like It

  • Offers a direct way to support histamine breakdown when food triggers are hard to avoid.
  • Useful for people who experience sensitivity to histamine-containing foods such as aged cheeses, red wine, or fermented products.
  • Simple, targeted formula with a single active ingredient—DAO.

Key Benefits

  • Helps break down food-derived histamine in the gut
  • Supports relief from histamine-related digestive and skin discomfort
  • Complements dietary approaches to histamine intolerance

What’s Inside

  • Diamine Oxidase (DAO) – The primary enzyme responsible for breaking down histamine in the small intestine, helping reduce histamine-related reactions from food.

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Supplement Facts & Suggested Use

Serving Size: 1 capsule

  • Diamine Oxidase (DAO) – 4.2 mg (20,000 HDU)

Other Ingredients: Microcrystalline cellulose, vegetarian capsule (hypromellose, water), ascorbyl palmitate.
Suggested Use: Take 1 capsule no more than 15 minutes before meals that contain histamine-rich foods (or as directed by your healthcare provider).

  • Not intended for continuous use as a maintenance supplement—best used as needed for meals.

Additional Resources

  • Research shows that supplementing with diamine oxidase can help reduce histamine-related food intolerance symptoms by supporting the body’s natural histamine breakdown process. Learn More
  • Doctor’s Reference Sheet: Learn More from Xymogen

Lifestyle Tip

Pairing HistDAO® with a low-histamine diet can make a big difference. Try limiting common triggers such as aged cheeses, cured meats, wine, and fermented foods. Keeping a food journal can also help you spot patterns and better manage symptoms.